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Our research is focused on understanding the molecular and cellular mechanisms driving regeneration processes in the CNS. We are specifically interested in cell responses driven by an altered environment in CNS disease with Blood-Brain Barrier opening. We aim to understand how changes in the environment regulate glial and fibrotic scar formation and neural stem cell differentiation and function. Our ultimate goal is to harness neural stem cells for resolving scar formation and improving CNS repair.  

 

We are using histopathology, microscopy, biochemistry, primary cell culture and animal models for CNS diseases with Blood-Brain Barrier opening to address the biological complexity of disease and repair mechanisms.

 

Ongoing Studies:

  • Mechanisms of Glial and Fibrotic scar formation
  • Neural Stem Cells for CNS Regeneration
  • Super Resolution Microscopy