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Prof. Dr. Tanja Vogel

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Prof. Dr. Tanja Vogel

Institute of Anatomy and Cell Biology
University of Freiburg
Albertstr. 17
D-79104 Freiburg

Tel.: +49-761-203 5086
Fax: +49-761-203 5091

E-Mail

 

Curriculum vitae

1. General Information  
Name Vogel, Tanja, Prof. Dr.
Position Professor (W3)
2. Scientific education  
10/1988-01/1994

Study of Biochemistry, University of Hannover

3. Scientific Education and Appointments  
07/1994-11/1997 PhD in human genetics, Instiute for Human Genetics, Hannover Medical School
2010 Habilitation in Anatomy, Universitäty Medicine Göttingen, Department of Neuroanatomy
4. Professional Career  
10/1997-01/2000 Postdoctoral fellow,MRC Human Genetics Unit, Edinburgh, UK
02/2000-07/2005 Postdoctoral fellow, MPI for Biophysical Chemistry, Göttingen
08/2005-03/2011 Group leader, Department of Neuroanatomy, Centre of Anatomy, University Medicine Göttingen
04/2011-01/2016 Associate Professor (W2), Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg
04/2014-10/2016 Managing Director of the Institute for Anatomy and Cell Biology, University of Freiburg
01/2016-present Professor (W3), Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg
5.Other Qualifications  
1994-1997 Doctoral fellowship from the DFG Graduate School “Molecular Pathophysiology of Cell Growth”
1998-2000 Travelling Research Fellowship of the Wellcome Trust, UK
2000-2001 Postdoctoral fellowship of the Max-Planck-Society
2011 Award for the best Habilitation of the University Medicine Göttingen

 

Current scientific research

Publications

Original paper

Hoffmann N, Weise SC, Marinaro F, Vogel T and De Pietri Tonelli D (2018) DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front. Neurosci. 12:281.

Bovio P, Roidl D, Heidrich S, Vogel T, Franz H (2018) Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark. J Vis Exp Jan 26;(131).

Grassi D, Franz H, Vezzali R, Bovio P, Heidrich S, Dehghanian F, Lagunas N, Belzung C, Krieglstein K, Vogel T (2017) Neuronal Activity, TGFβ-Signaling and Unpredictable Chronic Stress Modulate Transcription of Gadd45 Family Members and DNA Methylation in the Hippocampus. Cereb Cortex:1–16.
Ehrmann I, Gazzara MR, Pagliarini V, Dalgliesh C, Chadegani MK, Xu Y, Cesari E, Danilenko M, Maclennan M, Lowdon K, Vogel T, Keskivali-Bond P, Wells S, Cater H, Fort P, Koref MS, Middei S, Sette C, Clowry GJ, Barash Y, Cunningham M, Elliott DJ (2016) A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior. Cell Rep 17(12):3269-3280.

Seehusen FA, Kiel K, Jottini S, Wohlsein P, Habierski A, Seibel K, Vogel T, Urlaub H, Kollmar M, Baumgärtner W, Teichmann U (2016) Axonopathy in the Central Nervous System Is the Hallmark of Mice with a Novel Intragenic Null Mutation of Dystonin. Genetics. 204(1): 191-203.

Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T(2016) The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget, 7(25): 37436-37455.

Roidl D, Hellbach N, Bovio P, Villarreal A, Heidrich S, Nestel S, Grüning B, Bönisch U, Vogel T (2016) DOT1L activity promotes proliferation and protects cortical neural stem cells from activation of ATF4-DDIT3-mediated ER stress in vitro. Stem Cells 34(1):  233-45.

Kosinsky RL, Wegwitz F, Hellbach N, Dobbelstein M, Mansouri A, Vogel T, Begus-Nahrmann Y, Johnsen SA (2015) Usp22 deficiency impairs intestinal epithelial lineage specification in vivo. Oncotarget 6(35):37906-18.

Hellbach N, Weise SC, Vezzali R, Wahane SD, Heidrich S, Roidl D, Pruszak J, Esser JS, Vogel T (2014) Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. Hum Mol Genet 23(23):6177-90.

Wahane SD, Hellbach N, Prentzell MT, Weise SC, Vezzali R, Kreutz C, Timmer J, Krieglstein K, Thedieck K, Vogel T (2014) PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2. J Neurochem.130(2): 255-67.

Karpiuk O, Najafova Z, Kramer F, Hennion M, Galonska C, König A, Snaidero N, Vogel T, Shchebet TA, Begus-Nahrmann Y, Kassem M, Simons M, Shcherbata H, Beissbarth T, Johnsen SA (2012) The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Molecular Cell 46(5): 705–713.

Büttner N, Johnsen SA, Kügler S, Vogel T (2010) Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of upper layers in the cerebral cortex. Proc Natl Acad Sci U S A 107(15): 7042-7.

Overview articles

Vogel T, Lassmann S (2014) Epigenetics: development, dynamics and disease. Cell Tissue Res. 356:451-455.
Backofen R, Vogel T (2014) Biological and bioinformatical approaches to study crosstalk of long-non-coding RNAs and chromatin-modifying proteins. Cell Tissue Res. 356:507-526.
Roidl D, Hacker C (2014) Histone methylation during neural development. Cell Tissue Res. 356:539-552.
Vogel T, Schmidtke J (1998) Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein". Cytogenet Cell Genet 80: 209-213.

Publications 1996-1999

Publications 2000-2009

Book chapter
Insulin/IGF-Signalling in Embryonic and Adult Neural Proliferation and Differentiation in the Mammalian Central Nervous System

 

Scientific publications in Medline

Research Database University Freiburg

Other Ressources

NWG-Brain Project

www.usegalaxy.eu