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Prof. Dr. Tanja Vogel

Prof. Dr. Tanja Vogel

Institute of Anatomy and Cell Biology
University of Freiburg
Albertstr. 17
D-79104 Freiburg

Tel.: +49-761-203 5086
Fax: +49-761-203 5091

E-Mail

 

Curriculum vitae

1. General Information  
Name Vogel, Tanja, Prof. Dr.
Date of Birth 27.10.1969
Gender female
Position Professor (W3)
social state married, 2 children
2. Scientific education  
10/1988-01/1994

Study of Biochemistry, University of Hannover,
degree: "Diplom" Biochemistry, tutor: Prof. J. Schmidtke, University of Hannover

3. Scientific Education and Appointments  
07/1994-11/1997 PhD in human genetics, Instiute for Human Genetics, Hannover Medical School, tutor: Prof. J. Schmidtke
2010 Habilitation in Anatomy, Universitäty Medicine Göttingen, Department of Neuroanatomy, tutor: Prof. K. Krieglstein
4. Professional Career  
10/1997-01/2000 Postdoctoral fellow,MRC Human Genetics Unit, Edinburgh, UK, tutor: Prof. H.J. Cooke
02/2000-07/2005 Postdoctoral fellow, MPI for Biophysical Chemistry, Göttingen, tutor: Prof. P. Gruss
08/2005-03/2011 Group leader, Department of Neuroanatomy, Centre of Anatomy, Universitäty Medicine Göttingen
04/2011-01/2016 Associate Professor (W2), Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg
04/2014-10/2016 Managing Director of the Institute for Anatomy and Cell Biology, University of Freiburg
01/2016-present Professor (W3), Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg
5.Other Qualifications  
1994-1997 Doctoral fellowship from the DFG Graduate School “Molecular Pathophysiology of Cell Growth”
1998-2000 Travelling Research Fellowship of the Wellcome Trust, UK
2000-2001 Postdoctoral fellowship of the Max-Planck-Society
2011 Award for the best Habilitation of the University Medicine Göttingen
2007

Conference Organisation: Satellite Symposium:
Neural stem cells and neuronal specification, 31st Göttingen Neurobiology Conference and 7th Meeting of the German Neuroscience Society

Referee Activities  
  Referee for National Science Foundation (USA), Medical Research Council (UK), BBSRC(UK), INSERM (GIF), National Science Center (Poland).
  Journals: Cell and Tissue Research, Gene Expression Patterns, FEBS Letters, Journal of Vascular Research
Editorial Board member of The International Journal of Developmental Neuroscience

 

Current scientific research

Publications

Original Paper
  Original paper

1

Seehusen FA, Kiel K, Jottini S, Wohlsein P, Habierski A, Seibel K, Vogel T, Urlaub H, Kollmar M, Baumgärtner W, Teichmann U (2016) Axonopathy in the Central Nervous System Is the Hallmark of Mice with a Novel Intragenic Null Mutation of Dystonin. Genetics Early online July 8, 2016; DOI: 10.1534/genetics.116.186932

2

Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T(2016) The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget, May 21. doi: 10.18632/oncotarget.9545 [Epub ahead of print]

3

Roidl D, Hellbach N, Bovio P, Villarreal A, Heidrich S, Nestel S, Grüning B, Bönisch U, Vogel T (2016) DOT1L activity promotes proliferation and protects cortical neural stem cells from activation of ATF4-DDIT3-mediated ER stress in vitro. Stem Cells 34(1):233-45.

4

Roidl D, Hellbach N, Bovio P, Villarreal A, Heidrich S, Nestel S, Grüning B, Bönisch U, Vogel T (2015) DOT1L activity promotes proliferation and protects cortical neural stem cells from activation of ATF4-DDIT3-mediated ER stress in vitro. Stem Cells, doi: 10.1002/stem.2187.

5

Kosinsky RL, Wegwitz F, Hellbach N, Dobbelstein M, Mansouri A, Vogel T, Begus-Nahrmann Y, Johnsen SA (2015) Usp22 deficiency impairs intestinal epithelial lineage specification in vivo. Oncotarget 6(35):37906-18.

6

Vogel T, Lassmann S (2014) Epigenetics: development, dynamics and disease. Cell Tissue Res. 356:451-455.

7

Hellbach et al. 2014

8

Backofen R, Vogel T (2014) Biological and bioinformatical approaches to study crosstalk of long-non-coding RNAs and chromatin-modifying proteins. Cell Tissue Res. 356:507-526.

9

Wahane SD, Hellbach N, Prentzell MT, Weise SC, Vezzali R, Kreutz C, Timmer J, Krieglstein K, Thedieck K, Vogel T (2014) PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2. J Neurochem.[Epub ahead of print] PubMed PMID: 24645666.

10

Roidl D, Hacker C (2014) Histone methylation during neural development. Cell Tissue Res. 356:539-552.

11

Karpiuk O, Najafova Z, Kramer F, Hennion M, Galonska C, König A, Snaidero N, Vogel T, Shchebet TA, Begus-Nahrmann Y, Kassem M, Simons M, Shcherbata H, Beissbarth T, Johnsen SA (2012) The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Molecular Cell 46(5): 705–713.

12

Büttner N, Johnsen SA, Kügler S, Vogel T (2010) Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of upper layers in the cerebral cortex. Proc Natl Acad Sci U S A 107(15): 7042-7.

13

Vogel T, Ahrens S, Buttner N, Krieglstein K (2009) Transforming Growth Factor β Promotes Neuronal Cell Fate of Mouse Cortical and Hippocampal Progenitors In Vitro and In Vivo: Identification of Nedd9 as an Essential Signaling Component. Cereb Cortex 20(3): 661-71.

14

Schulz R, Vogel T, Mashima T, Tsuruo T, Krieglstein K (2009) Involvement of fractin in TGF-beta-induced apoptosis in oligodendroglial progenitor cells. Glia 57(15): 1619-29.

15

Vogel T, Gruss P (2009) Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr.Patterns 9: 83-93.

16

Schulz R, Vogel T, Dressel R, Krieglstein K (2008) TGF-beta superfamily members, ActivinA and TGF-beta1, induce apoptosis in oligodendrocytes by different pathways. Cell Tissue Res 334: 327-338.

17

Britanova O, de Juan RC, Cheung A, Kwan KY, Schwark M, Gyorgy A, Vogel T, Akopov S, Mitkovski M, Agoston D, Sestan N, Molnar Z, Tarabykin V (2008) Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron 57: 378-392.

18

Vogel T, Stoykova A, Gruss P (2006) Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes. Dev Dyn 235: 2574-2585.

19

Vogel T, Speed RM, Ross A, Cooke HJ (2002) Partial rescue of the Dazl knockout mouse by the human DAZL gene. Mol Hum Reprod 8: 797-804.

20

Tascou S, Nayernia K, Samani A, Schmidtke J, Vogel T, Engel W, Burfeind P (2000) Immortalization of murine male germ cells at a discrete stage of differentiation by a novel directed promoter-based selection strategy. Biol Reprod 63: 1555-1561.

 

Overview articles

 

Vogel T, Lassmann S (2014) Epigenetics: development, dynamics and disease. Cell Tissue Res. 356:451-455.

 

Backofen R, Vogel T (2014) Biological and bioinformatical approaches to study crosstalk of long-non-coding RNAs and chromatin-modifying proteins. Cell Tissue Res. 356:507-526.

 

Roidl D, Hacker C (2014) Histone methylation during neural development. Cell Tissue Res. 356:539-552.

 

Vogel T, Schmidtke J (1998) Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein". Cytogenet Cell Genet 80: 209-213.

 

Publications 1996-1999

 

  Book chapter
  Insulin/IGF-Signalling in Embryonic and Adult Neural Proliferation and Differentiation in the Mammalian Central Nervous System

 

Scientific publications in Medline

Research Database University Freiburg

Other Ressources

NWG-Brain Project